Filtration Principles

The primary objective of breathing filters is to stop bacteria and viruses entering/leaving the patient. Electrostatic filters achieve this by holding onto micro-organisms through the static electric charge in the medium. The pleated paper filter also known as a mechanical filter achieves this by tightly packed layers of mixed strands of glass fibres physically preventing bacteria and viruses from passing through.


HME's use the patients own moisture and humidity from expiration to humidify anesthetic gases during inspiration. When endotracheal tubes are used, the upper airway that usually warms inspired air is bypassed and for patients that are anticipated to be under anesthesia for long periods or ventilated patients, it is recommended that an HME/HMEF be used as prolonged dry gas exposure can have adverse effects.


The descriptions and diagrams below show a detailed example of Electrostatic Filters and Mechanical Filters.

 

Electrostatic Filters
Electrostatic filters use a medium constructed of permanently bipolar charged rectangular split fibres which are able to capture airborne particles. The nature of this fibre material provides good strength and guarantees a long service life without significant degradation. This type of filter is recommended for applications where high efficiency and low pressure drop is required. It offers excellent efficiency for anesthetic breathing filters and pulmonary function filters.
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Mechanical Filters
Pleated paper filters use tightly packed layers of mixed strands of glass fibre filter paper. This non-uniform method of packing produces a thick layer of material. Particles are trapped in the tortuous path created by the crisscross mat. In principle, the medium used acts as a sieve, holding back unwanted particles while allowing anaesthetic gases and humidified air to travel through with minimum obstruction.
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Efficiency Testing
The effectiveness of a filter is stated as a percentage (%) efficiency and is defined as:

 

cfu or pfu collected without BSF in place - cfu or pfu with BSF in place x100
cfu or pfu without BSF in place
cfu = colony forming units, pfu = plaque forming units, BSF = breathing system filter


Efficiency is measured by microbial penetration value which is defined as the number of colony forming units or plaque forming units passing through the filter per 10,000,000 challenge micro-organisms.


To test a filter for bacterial efficiency the filter is subjected to a preconditioning of 24 hours under relative humidity of 96%
or more and temperature of 34° ± 1 at a tidal volume of 500ml at 20 breaths per minute with I/E ratio of 1:2. Following this
preconditioning the filters are challenged with microbial aerosols using the Henderson Apparatus to deliver a challenge of over 10,000,000 Bacillus Subtillis Var.Niger Spores (NCTC10073). For viral efficiency a RNA-Phage (MS-2 Coliphage) which is similar to the smallest human viruses is to be used to test the efficiency of the filter. The test results certify the proven high efficiency of Flexicare filters.


The efficiency of the Flexicare and HepaShield filter is tested by the Health Protection Agency at Porton Down, Salisbury, UK. Testing was done for bacterial and viral efficiency using Bacillus Subtillis and MS-2 Coliphage.

 

The diagram below highlights the size of test particles used in evaluating the efficiency of the Flexicare Filter.

 

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Independent tests confirm that the Flexicare range of breathing filters prevent bacteria and viruses from passing between patients and ventilator equipment.

 

Dead Space
This is the internal air filled volume of the filter or HMEF. Dead Space contributes to the compliance of the breathing system as filters are placed between breathing systems and the patient.


Moisture Output
This may be an important requirement for some patients who are being intubated over a long period of time. The unfortunate consequence of intubation is that the upper airway is bypassed and results in a loss of humidification of inspired air. Dry gases can have adverse effects and thus to prevent causing the patient trauma HMEF's play the role of acting as the humidifier in lieu of the upper airway. However, humidification can cause rain-out in either direction. Flexicare Filter medium has a double sided hydrophobic membrane which repels water and helps to maintain effective performance of the filter during its use.

Construction
The diagram below shows the construction of the Adult Electrostatic Breathing Filter with HME

 

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